I think it depends on the way it interacts with your OpenType layout features. It might be best to only have one, but if that makes your features too complex, then it might be wise to have multiple.
The only one I need is that simple glyph, white, to force the interior of the note to be white. What I need is for it to be shifted vertically in several different iterations, and I can’t figure that part out.
If I have the glyph created, how can I add it to those different locations?
Also, when I tried creating one, it seemed like it broke some things. You mentioned features. Does COLR cause complcations with other OpenType functions? If so, that’s not a new complexity I want to introduce. This font is already getting pretty complicated.