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If you have the Professional Edition, you can run a transform script to make the letters bolder, but it usually takes a lot more work than simply running the script. That depends on the typeface design. See the tutorials on Glyph Transformations
Typically, if a font has serifs, the serifs will be much too bold after the transformation. Nodes will have to be manually selected and moved to reduce the weight of the serifs and other thin strokes to suit the bold font style. Cursive scripts are even more problematic.
